Synthesis, Characterization and Anticancer Activity Studies of New Schiff Base Pt (II) Complex
| dc.contributor.author | Al-Aghbari, Sama A. | |
| dc.contributor.author | Al-Shuja'a, Omar M. | |
| dc.contributor.author | Al-Badani, Rowaida | |
| dc.contributor.author | Japir, Abd Al-Wali M. | |
| dc.date.accessioned | 2026-06-17T00:22:21Z | |
| dc.date.issued | 2019 | |
| dc.description.abstract | A New Schiff base ligand and its Pt (II) complex were synthesized. The ligand was prepared by condensation of 2-(4-isobutylphenyl)propanehydrazide with 2,3,4-trihydroxy benzaldehyde this novel ligand and its functional group was carefully designed and selected from well-known biological drugs. The structure of the ligand and its Pt-complex have been confirmed by spectroscopic data, i.e. elemental (CHN) analysis, FT-IR, electronic spectra, NMR spectra. The ligand and its Pt-complex were investigated for their in vitro anticancer potential using HeLa and PC3 cells. The Pt-complex showed a higher cytotoxic activity than the ligand towards Hela cells and PC3 cells. | en_US |
| dc.identifier | 10.4236/msce.2019.78001 | |
| dc.identifier.citation | Al-Aghbari, S. A., Al-Shuja'a, O. M., Al-Badani, R., & Japir, A. A.-W. M. (2019). Synthesis, characterization and anticancer activity studies of new Schiff base Pt (II) complex.�Journal of Materials Science and Chemical Engineering,�7, 1-8.�https://doi.org/10.4236/msce.2019.78001 | en_US |
| dc.identifier.uri | https://repository.ust.edu.ye/handle/123456789/538 | |
| dc.identifier.uri | https://www.scirp.org/html/1-1740706_94137.htm | |
| dc.language.iso | en | |
| dc.publisher | Scientific Research Publishing | en_US |
| dc.title | Synthesis, Characterization and Anticancer Activity Studies of New Schiff Base Pt (II) Complex | en_US |
| dc.type | Article | en_US |