Chemical Composition and Biological Activity of Lavandula pubescens Essential Oil from Yemen
| dc.contributor.author | Al-Badani, Rowaida N. | |
| dc.contributor.author | da Silva, Joyce Kelly R. | |
| dc.contributor.author | Mansi, Iman | |
| dc.contributor.author | Muharam, Bushra A. | |
| dc.contributor.author | Setzer, William N. | |
| dc.contributor.author | Awadh Ali, Nasser A. | |
| dc.date.accessioned | 2026-06-29T02:26:01Z | |
| dc.date.issued | 2017 | |
| dc.description.abstract | The chemical composition of the hydrodistilled aerial parts of essential oil from Lavandula pubescens Decne. collected from Imran in Yemen was determined by GC-MS analysis, and its cytotoxic, xanthine oxidase inhibitory, antiradical and antimicrobial activities were evaluated. The main compounds were carvacrol (72.7 %), carvacrol methyl ether (7.0 %) and caryophyllene oxide (5.9 %). The oil exhibited strong cytotoxicity against Hela (cervical) and AGS (gastric) cell lines with IC50 less than 10 ?g/mL. It is also had excellent xanthine oxidase (XO) inhibitory activity with % inhibition of 26.1 % at 10 ?g/ml and IC50 of 3.8 ?g/mL. The oil demonstrated strong antiradical activity with IC50 value of 75.08 ?g/mL in addition to highest antibacterial activity against Staphylococcus aureus, Micrococcus luteus, and Escherichia coli with MIC value of 0.078 ?L/mL. | en_US |
| dc.identifier | 10.1080/0972060X.2017.1322538 | |
| dc.identifier.citation | Al-Badani, R. N., da Silva, J. K. R., Mansi, I., Muharam, B. A., Setzer, W. N., & Awadh Ali, N. A. (2017). Chemical composition and biological activity of Lavandula pubescens essential oil from Yemen. Journal of Essential Oil Bearing Plants, 20(2), 509-515. https://doi.org/10.1080/0972060X.2017.1322538 | en_US |
| dc.identifier.uri | https://www.tandfonline.com/doi/abs/10.1080/0972060X.2017.1322538 | |
| dc.identifier.uri | https://repository.ust.edu.ye/handle/123456789/2086 | |
| dc.language.iso | en | |
| dc.publisher | Taylor & Francis | en_US |
| dc.title | Chemical Composition and Biological Activity of Lavandula pubescens Essential Oil from Yemen | en_US |
| dc.type | Article | en_US |